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KMID : 0390220000110010092
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Journal of Clinical Otolaryngology, Head and Neck Surgery
2000 Volume.11 No. 1 p.92 ~ p.97
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Clinical Considerations of Kikuchi's Disease
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최충식/Choong Sik Choi
최건/조재훈/정광윤/최종욱/Geon Choi/Jae Hoon Cho/Kwang Yoon Jung/Jong Ouck Choi
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Abstract
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Background and Objectives : Kikuchi's disease, also known as various terms, is the benign self limiting disease
of unknown origin. It causes cervical lymphadenitis, usually in young women with frequent fever. Also it may be
mistaken for malignant lymphoma or ther systemic granulomatous inflammatory disease. The purpose of this
study is to report the characteristics of clinical, laboratory and pathologic findings of Kikuchi's disease. Materials
and Methods : We evaluated 29 patients, who were diagnosed as Kikuchi's disease with excisional biopsies,
retrospectively. Results: There was female predilection and the most common presenting symptoms was fever.
The common involvement site were superior and inferior internal jugular chain and spinal accessory chain.
Laboratory findings revealed that leukopenia and high ESR(erythrocyte sedimentation rate) were noted and
admixture of monocyte and histiocyte with karyorrhetic debris were observed in the biopsy specimen. Only two
of twelve case were positive finding of Kikuchi's disease on fine-needle aspiration cytology. Conclusions : We
descirbed 29 cases of Kikuchi's disease with clinical, laboratory and pathologic findings and reviewed the
literature. And it will be needed further study to improve the technique and accuracy of fine-needle aspiration
cytology.
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KEYWORD
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